Research Use Only·Third-Party Analytical Testing·COA Available·Authorized Researchers OnlyResearch Use Only · COA Available · Authorized Researchers
peptide-solutions
ERRα/β/γ agonist for exercise mimetic research
Research Compound
Manufactured under strict quality control protocols with full analytical testing. Certificate of Analysis (COA) available upon request.
SLU-PP-332 is a small-molecule pan-agonist of estrogen-related receptors ERRα, ERRβ, and ERRγ. Research highlights its potential as an exercise mimetic with profound effects on skeletal muscle mitochondrial biogenesis.
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Amount per vial: 1 unit
Scientific Documentation
Detailed research information, pharmacological profile, and handling specifications
4-Hydroxy-N-[(E)-naphthalen-2-ylmethylideneamino]benzamideSLU-PP-332 functions as a synthetic pan-ERR agonist that potently activates the ERRα, ERRβ, and ERRγ nuclear receptors. This activation triggers a robust transcriptional cascade that upregulates PGC-1α, the primary driver of Mitochondrial Biogenesis in skeletal and cardiac tissues. • Oxidative Remodeling: The compound drives a phenotypic shift toward Oxidative Muscle Fibers (Type IIa), increasing mitochondrial density and cellular respiratory capacity. • PDK4 Activation: By inducing PDK4 expression, SLU-PP-332 redirects cellular metabolism toward Fatty Acid Oxidation, mimicking the acute aerobic exercise response. • Genomic Programming: It activates an "aerobic program" that enhances the expression of genes involved in the citric acid cycle and oxidative phosphorylation, ultimately increasing Endurance Capacity and protecting against metabolic dysfunction.
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This product is intended strictly for laboratory and research purposes only. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm that you are an authorized researcher or institution and that this product will be used solely for legitimate research purposes in compliance with all applicable laws and regulations.
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