peptide-solutions

TB-500

Thymosin β-4 fragment for tissue repair and regeneration research

Research Compound

Manufactured under strict quality control protocols with full analytical testing. Certificate of Analysis (COA) available upon request.

Purity: >98%Form: LyophilizedStorage: -20°CGrade: Research

New

TB-500 is a synthetic peptide based on the active region of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid peptide involved in actin sequestration and cellular migration. Research applications focus on tissue repair, angiogenesis, anti-inflammatory pathways, and wound-healing models — frequently paired with BPC-157 in regeneration protocols.

Compound Specifications

Purity Level>98%

Physical FormLyophilized powder (10mg/vial)

CAS Number77591-33-4

Sequence / StructureAc-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

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Amount per vial: 10mg

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Third-Party Tested

Scientific Documentation

Research Reference

Detailed research information, pharmacological profile, and handling specifications

Mechanism of Action

Sequence / Structure

Ac-Ser-Asp-Lys-Pro-Asp-Met-Ala-Glu-Ile-Glu-Lys-Phe-Asp-Lys-Ser-Lys-Leu-Lys-Lys-Thr-Glu-Thr-Gln-Glu-Lys-Asn-Pro-Leu-Pro-Ser-Lys-Glu-Thr-Ile-Glu-Gln-Glu-Lys-Gln-Ala-Gly-Glu-Ser

TB-500 binds and sequesters G-actin monomers, regulating actin polymerization and cytoskeletal dynamics. This drives cell migration, angiogenesis (via VEGF / angiopoietin signaling), and a tissue-repair phenotype across endothelial, epithelial, and stem-cell populations. Downstream effects on inflammatory cytokine balance and recruitment of progenitor cells to injury sites have been characterized across the published wound-healing literature.

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Research Use Only Disclaimer

This product is intended strictly for laboratory and research purposes only. Not for human or veterinary use. Not intended to diagnose, treat, cure, or prevent any disease. By purchasing, you confirm that you are an authorized researcher or institution and that this product will be used solely for legitimate research purposes in compliance with all applicable laws and regulations.